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DB00554 : piroxicam

Approved drug piroxicam ... 2 targets DB00554

Generic name: piroxicam
 
Brand name(s): akten, apo-piroxicam, artroxicam, baxo, bruxicam, caliment, erazon, feldene, flogobene, geldene, improntal, larapam, pipoxicam, pirkam, piroflex, reudene, riacen, roxicam, roxiden, sasulen, solocalm, zunden, piroxicam usp.
Formula: C15H13N3O4S
IUPAC Formula: 4-Hydroxy-2-Methyl-1,1-Dioxo-N-(Pyridin-2-Yl)-2h-1l^{6},2-Benzothiazine-3-Carboxamide

2
There are 2 target proteins defined in DrugBank for this drug.
 1 
1 of these target proteins has one or more structures in the PDB.
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Target proteins

DrugBank drug Target 1:   UniProt id: P35354 (PGH2_HUMAN)  -  Prostaglandin G/H synthase 2
UniProt id: P35354    603 a.a.  
1v0x A     604 a.a. 603   Theor. model
There are no PDB entries containing piroxicam bound to this target protein, although there is 1 entry of the target protein in the PDB (see above).
DrugBank drug Target 2:   UniProt id: P23219 (PGH1_HUMAN)  -  Prostaglandin G/H synthase 1
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)

Key:    PfamA domain  Secondary structure  Bound drug molecule

 

 

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