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DB00514 : dextromethorphan

Approved drug dextromethorphan ... 5 targets DB00514

Generic name: dextromethorphan
 
Brand name(s): antussan, balminil dm, balminil dm children, benylin adult formula cough suppressant, benylin dm, benylin dm 12 hour, benylin dm for children, benylin dm for children 12 hour, benylin pediatric cough suppressant, calmylin #1, canfodion, cosylan, cough-x, creo-terpin, delsym, delsym cough formula, diabe-tuss dm syrup, dormetan, dormethan, hihustan m., hold dm, koffex dm, medicon, methorate hydrobromide, methorphan, metrorat, novahistex dm, novahistine dm, pertussin cs children's strength, pertussin dm extra strength, robitussin maximum strength cough suppressant, robitussin pediatric, robitussin pediatric cough suppressant, romilar, sucrets 4 hour cough suppressant, triaminic dm long lasting for children, trocal, tusilan, tussade, vicks 44 cough relief.
Formula: C18H25No
IUPAC Formula: (1r,9r,10r)-4-Methoxy-17-Methyl-17-Azatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2,4,6-Triene

5
There are 5 target proteins defined in DrugBank for this drug.
Links  
DrugBank
ChEBI
KEGG drug
PubChem
Information  
Pharmacology
Indication
Action

 

Target proteins

DrugBank drug Target 1:   UniProt id: Q99720 (SGMR1_HUMAN)  -  Sigma 1-type opioid receptor
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 2:   UniProt id: Q5T1J1 (Q5T1J1_HUMAN)  -  Opioid receptor, sigma 1
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 3:   UniProt id: Q8TCU5 (NMD3A_HUMAN)  -  Glutamate [NMDA] receptor subunit 3A
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 4:   UniProt id: Q15822 (ACHA2_HUMAN)  -  Neuronal acetylcholine receptor subunit alpha-2
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 5:   UniProt id: P31645 (SC6A4_HUMAN)  -  Sodium-dependent serotonin transporter
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)

Key:  

 

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