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DB00499 : flutamide

Approved drug flutamide ... 2 targets DB00499

Generic name: flutamide
 
Brand name(s): cebatrol, eulexin, niftholide, niftolide.
Formula: C11H11F3N2O3
IUPAC Formula: 2-Methyl-N-[4-Nitro-3-(Trifluoromethyl)phenyl]propanamide

2
There are 2 target proteins defined in DrugBank for this drug.
 1 
1 of these target proteins has one or more structures in the PDB.
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Target proteins

DrugBank drug Target 1:   UniProt id: P10275 (ANDR_HUMAN)  -  Androgen receptor
UniProt id: P10275    918 a.a.  
1. 1xj7 A     256 a.a. 256   X-ray 2.70 Å
  2. 1t65 A     251 a.a. 251   X-ray 1.66 Å
  3. 2am9 A     250 a.a. 250   X-ray 1.64 Å
  4. 2pit A     250 a.a. 250   X-ray 1.76 Å
  5. 1t63 A     250 a.a. 250   X-ray 2.07 Å
   more ...
There are no PDB entries containing flutamide bound to this target protein, although there are 76 entries of the target protein (click the orange, plus icon for a list).
DrugBank drug Target 2:   UniProt id: P35869 (AHR_HUMAN)  -  Aryl hydrocarbon receptor
UniProt id: P35869    848 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)

Key:    PfamA domain  PfamB domain  Secondary structure  Bound drug molecule

 

 

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