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DB00407 : ardeparin

Approved drug ardeparin ... 2 targets DB00407

Generic name: ardeparin
 
Brand name(s): normiflo.
Formula: C26H42N2O37S5
IUPAC Formula: 3-[(5-{[6-Carboxy-4,5-Dihydroxy-3-(Sulfooxy)oxan-2-Yl]oxy}-6-(Hydroxymethyl)-3-(Sulfoamino)-4-
(Sulfooxy)oxan-2-Yl)oxy]-6-({5-Acetamido-4,6-Dihydroxy-2-[(Sulfooxy)methyl]oxan-3-Yl}oxy)-4-Hydroxy-
5-(Sulfooxy)oxane-2-Carboxylic acid

2
There are 2 target proteins defined in DrugBank for this drug.
 2 
2 of these target proteins have one or more structures in the PDB.
Links  
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Target proteins

DrugBank drug Target 1:   UniProt id: P01008 (ANT3_HUMAN)  -  Antithrombin-III
UniProt id: P01008    463 a.a.  
1. 1dzg I,L     422 a.a. 420   X-ray 2.80 Å
  2. 3kcg I     419 a.a. 418   X-ray 1.70 Å
  3. 1e03 I,L     418 a.a. 418   X-ray 2.90 Å
  4. 1e05 I,L     417 a.a. 417   X-ray 2.62 Å
  5. 1azx I,L     417 a.a. 417   X-ray 2.90 Å
   more ...
There are no PDB entries containing ardeparin bound to this target protein, although there are 27 entries of the target protein (click the orange, plus icon for a list).
DrugBank drug Target 2:   UniProt id: P05546 (HEP2_HUMAN)  -  Heparin cofactor 2
UniProt id: P05546    498 a.a.  
1. 1jmo A     425 a.a. 423   X-ray 2.20 Å
  2. 1jmj A,B     397 a.a. 397   X-ray 2.35 Å
There are no PDB entries containing ardeparin bound to this target protein, although there are 2 entries of the target protein (click the orange, plus icon for a list).

Key:    PfamA domain  PfamB domain  Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

 

Structure selection

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