spacer
spacer

Search 

DB00354 : buclizine

Approved drug buclizine ... 2 targets DB00354

Generic name: buclizine
 
Brand name(s): aphilan r, aphilan-r base, bucladin, bucladin-s, buclifen, buclina, buclodin, histabuticine, histabutizine, histabutyzine, histabutyzine dihydrochloride, histabutyzine hydrochloride, hitabutyzyne, longifene, posdel, postafen, softran, vibazine.
Formula: C28H33Cln2
IUPAC Formula: 1-[(4-Tert-Butylphenyl)methyl]-4-[(4-Chlorophenyl)(phenyl)methyl]piperazine

2
There are 2 target proteins defined in DrugBank for this drug.
 1 
1 of these target proteins has one or more structures in the PDB.
Links  
DrugBank
ChEBI
PubChem
Information  
Pharmacology
Indication
Action

 

Target proteins

DrugBank drug Target 1:   UniProt id: P35367 (HRH1_HUMAN)  -  Histamine H1 receptor
UniProt id: P35367    487 a.a.  
   more ...
There are no PDB entries containing buclizine bound to this target protein, although there is 1 entry of the target protein in the PDB (see above).
DrugBank drug Target 2:   UniProt id: P11229 (ACM1_HUMAN)  -  Muscarinic acetylcholine receptor M1
UniProt id: P11229    460 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)

Key:    PfamA domain

 

  spacer

spacer