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DB00348 : nitisinone

Approved drug nitisinone ... 1 target DB00348

Generic name: nitisinone
 
Brand name(s): orfadin.
Formula: C14H10F3No5
IUPAC Formula: 2-{[2-Nitro-4-(Trifluoromethyl)phenyl]carbonyl}cyclohexane-1,3-Dione

1
There is 1 target protein defined in DrugBank for this drug.
 1 
The target protein has one or more structures in the PDB.
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Target proteins

DrugBank drug Target 1:   UniProt id: P32754 (HPPD_HUMAN)  -  4-hydroxyphenylpyruvate dioxygenase
UniProt id: P32754    392 a.a.  
3isq A     376 a.a. 376   X-ray 1.75 Å
There are no PDB entries containing nitisinone bound to this target protein, although there is 1 entry of the target protein in the PDB (see above).

Key:    PfamA domain  Secondary structure  Bound drug molecule

 

 

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