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DB00304 : desogestrel

Approved drug desogestrel ... 2 targets DB00304

Generic name: desogestrel
 
Brand name(s): cerazette.
Formula: C22H30O
IUPAC Formula: (1s,2r,10s,11s,14r,15s)-15-Ethyl-14-Ethynyl-17-
Methylidenetetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-En-14-Ol

2
There are 2 target proteins defined in DrugBank for this drug.
 2 
2 of these target proteins have one or more structures in the PDB.
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Target proteins

DrugBank drug Target 1:   UniProt id: P06401 (PRGR_HUMAN)  -  Progesterone receptor
UniProt id: P06401    932 a.a.  
1. 1a28 A,B     251 a.a. 251   X-ray 1.80 Å
  2. 2w8y A,B     251 a.a. 251   X-ray 1.80 Å
  3. 1zuc B,A     251 a.a. 251   X-ray 2.00 Å
  4. 1e3k A,B     251 a.a. 251   X-ray 2.80 Å
  5. 3zr7 A,B     250 a.a. 250   X-ray 1.65 Å
   more ...
There are no PDB entries containing desogestrel bound to this target protein, although there are 20 entries of the target protein (click the orange, plus icon for a list).
DrugBank drug Target 2:   UniProt id: P03372 (ESR1_HUMAN)  -  Estrogen receptor
UniProt id: P03372    594 a.a.  
1. 1qku A,B,C     250 a.a. 250   X-ray 3.20 Å
  2. 3ert A     247 a.a. 247   X-ray 1.90 Å
  3. 1g50 A,B,C     247 a.a. 247   X-ray 2.90 Å
  4. 2ouz A     246 a.a. 246   X-ray 2.00 Å
  5. 3erd A,B     246 a.a. 246   X-ray 2.03 Å
   more ...
There are no PDB entries containing desogestrel bound to this target protein, although there are 104 entries of the target protein (click the orange, plus icon for a list).

Key:    PfamA domain  Secondary structure  Bound drug molecule

 

 

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