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DB00291 : chlorambucil

Approved drug chlorambucil ... 1 target DB00291

Generic name: chlorambucil PDB Het Group: CBL
 
2 structures in PDB
Brand name(s): ambochlorin, amboclorin, ecloril, elcoril, leukeran, leukeran tablets, leukersan, leukoran, linfolizin, linfolysin, pepstatin.
Formula: C14H19Cl2No2
IUPAC Formula: 4-{4-[Bis(2-Chloroethyl)amino]phenyl}butanoic acid
PDB name: Chlorambucil

1
There is 1 target protein defined in DrugBank for this drug.
 1 
There is 1 PDB structure containing the drug molecule bound to a protein that is not specified as a target.
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Target proteins

DrugBank drug Target 1:   Bacterial outer membrane
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)

Key:  

 

Other proteins with chlorambucil bound in the PDB

There is 1 "non-target" protein in the PDB containing the chlorambucil molecule bound. That is, the UniProt code for the protein is missing or does not match the drug target above.

Protein 1:   UniProt id: P09211 ()  -  Glutathione S-transferase P OS=Homo sapiens GN=GSTP1 PE=1 SV=2
UniProt id: P09211    209 a.a.  
21gs A,B   208 a.a. 208   X-ray 1.90 Å
The PDB contains 1 entry of chlorambucil bound to this protein

Key:    PfamA domain  Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

Structure selection

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