spacer
spacer

Search 

DB00216 : eletriptan

Approved drug eletriptan ... 7 targets DB00216

Generic name: eletriptan
 
Brand name(s): relpax.
Formula: C22H26N2O2S
IUPAC Formula: 5-[2-(Benzenesulfonyl)ethyl]-3-{[(2r)-1-Methylpyrrolidin-2-Yl]methyl}-1h-Indole

7
There are 7 target proteins defined in DrugBank for this drug.
 2 
2 of these target proteins have one or more structures in the PDB.
Links  
DrugBank
RxList
ChEBI
KEGG drug
PubChem
Information  
Pharmacology
Indication
Action

 

Target proteins

DrugBank drug Target 1:   UniProt id: P28221 (5HT1D_HUMAN)  -  5-hydroxytryptamine 1D receptor
UniProt id: P28221    377 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 2:   UniProt id: P28222 (5HT1B_HUMAN)  -  5-hydroxytryptamine 1B receptor
UniProt id: P28222    389 a.a.  
2g1x A     390 a.a. 389   Theor. model
There are no PDB entries containing eletriptan bound to this target protein, although there are 3 entries of the target protein (click the orange, plus icon for a list).
DrugBank drug Target 3:   UniProt id: P30939 (5HT1F_HUMAN)  -  5-hydroxytryptamine 1F receptor
UniProt id: P30939    366 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 4:   UniProt id: P08908 (5HT1A_HUMAN)  -  5-hydroxytryptamine 1A receptor
UniProt id: P08908    422 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 5:   UniProt id: P28566 (5HT1E_HUMAN)  -  5-hydroxytryptamine 1E receptor
UniProt id: P28566    365 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank drug Target 6:   UniProt id: P41595 (5HT2B_HUMAN)  -  5-hydroxytryptamine 2B receptor
UniProt id: P41595    481 a.a.  
   more ...
There are no PDB entries containing eletriptan bound to this target protein, although there are 2 entries of the target protein (click the orange, plus icon for a list).
DrugBank drug Target 7:   UniProt id: P34969 (5HT7R_HUMAN)  -  5-hydroxytryptamine 7 receptor
UniProt id: P34969    479 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)

Key:    PfamA domain  PfamB domain  Secondary structure  Bound drug molecule

 

 

Structure selection

Use the checkboxes above to select the structure(s) of interest, and then press the required button below to view:
View 3D structure
Select preferred viewer and click on 3D struct button
AstexViewer™@MSD-EBI
RasMol
STRAP multiple alignment viewer

  spacer

spacer