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DB00212 : remikiren

Approved drug remikiren ... 1 target DB00212

Generic name: remikiren PDB Het Group: REM
 
1 structure in PDB
Brand name(s): none.
Formula: C33H50N4O6S
IUPAC Formula: (2s)-2-[(2r)-2-Benzyl-3-(2-Methylpropane-2-Sulfonyl)propanamido]-N-[(2r,3s,4r)-1-Cyclohexyl-4-
Cyclopropyl-3,4-Dihydroxybutan-2-Yl]-3-(1h-Imidazol-5-Yl)propanamide
PDB name: Nalpha-[(2s)-2-Benzyl-3-(Tert-Butylsulfonyl)propanoyl]-N-[(1s,2r,3s)-1-(Cyclohexylmethyl)-3-
Cyclopropyl-2,3-Dihydroxypropyl]-L-Histidinamide

1
There is 1 target protein defined in DrugBank for this drug.
 1 
The target protein has one or more structures in the PDB.
 1 
There is 1 PDB structure of the drug molecule bound to its target protein.
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Target proteins

DrugBank drug Target 1:   UniProt id: P00797 (RENI_HUMAN)  -  Renin
UniProt id: P00797    405 a.a.  
3d91 A,B   334 a.a. 333   X-ray 2.20 Å
The PDB contains 1 entry of remikiren bound to this target protein and 67 entries of this target protein in all (click on orange, plus icon for list).

Key:    PfamA domain  Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

 

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