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DB00196 : fluconazole

Approved drug fluconazole ... 1 target DB00196

Generic name: fluconazole PDB Het Group: TPF
 
1 structure in PDB
Brand name(s): biocanol, biozolene, diflucan, elazor, flucazol, flucostat, flukezol, flunizol, pritenzol, triflucan.
Formula: C13H12F2N6O
IUPAC Formula: 2-(2,4-Difluorophenyl)-1,3-Bis(1h-1,2,4-Triazol-1-Yl)propan-2-Ol
PDB name: 2-(2,4-Difluorophenyl)-1,3-Di(1h-1,2,4-Triazol-1-Yl)propan-2-Ol

1
There is 1 target protein defined in DrugBank for this drug.
 1 
There is 1 PDB structure containing the drug molecule bound to a protein that is not specified as a target.
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Target proteins

DrugBank drug Target 1:   UniProt id: P10613 (CP51_CANAL)  -  Cytochrome P450 51
UniProt id: P10613    528 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)

Key:    PfamA domain

 

Other proteins with fluconazole bound in the PDB

There is 1 "non-target" protein in the PDB containing the fluconazole molecule bound. That is, the UniProt code for the protein is missing or does not match the drug target above.

Protein 1:   UniProt id: P9WPP7 ()  -  Mycocyclosin synthase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) GN=cyp121 PE=1 SV=1
  No Pfam domain assignments available for this protein.
2ij7 A,B,C,D,...   391 a.a. 391   X-ray 1.90 Å
The PDB contains 1 entry of fluconazole bound to this protein

Key:    Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

Structure selection

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