spacer
spacer

Search 

DB00178 : ramipril

Approved drug ramipril ... 1 target DB00178

Generic name: ramipril
 
Brand name(s): acovil, altace, carasel, cardace, delix, hypren, hytren, lostapres, pramace, quark, ramace, triatec, tritace, vesdil.
Formula: C23H32N2O5
IUPAC Formula: (2s,3as,6as)-1-[(2s)-2-{[(2s)-1-Ethoxy-1-Oxo-4-Phenylbutan-2-Yl]amino}propanoyl]-
Octahydrocyclopenta[b]pyrrole-2-Carboxylic acid

1
There is 1 target protein defined in DrugBank for this drug.
 1 
The target protein has one or more structures in the PDB.
Links  
DrugBank
RxList
ChEBI
KEGG drug
PubChem
Information  
Pharmacology
Indication
Action

 

Target proteins

DrugBank drug Target 1:   UniProt id: P12821 (ACE_HUMAN)  -  Angiotensin-converting enzyme
UniProt id: P12821    1305 a.a.  
1. 2c6n A,B     612 a.a. 612   X-ray 3.00 Å
  2. 2c6f A,B     612 a.a. 612   X-ray 3.01 Å
  3. 4bzs A,B     612 a.a. 611   X-ray 2.10 Å
  4. 4ca6 A,B     608 a.a. 601   X-ray 1.91 Å
  5. 3nxq A,B     607 a.a. 600   X-ray 1.99 Å
   more ...
There are no PDB entries containing ramipril bound to this target protein, although there are 28 entries of the target protein (click the orange, plus icon for a list).

Key:    PfamA domain  Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

 

Structure selection

Use the checkboxes above to select the structure(s) of interest, and then press the required button below to view:
View 3D structure
Select preferred viewer and click on 3D struct button
AstexViewer™@MSD-EBI
RasMol
STRAP multiple alignment viewer
LIGPLOT diagrams
Press button below for LIGPLOT diagrams of drug-protein interactions in all selected structures above.

  spacer

spacer