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DB00174 : l-asparagine

Approved nutraceutical l-asparagine ... 6 targets DB00174

Generic name: l-asparagine
 
Brand name(s): agedoite, altheine, crystal vi.
Formula: C4H8N2O3
IUPAC Formula: (2s)-2-Amino-3-Carbamoylpropanoic acid

6
There are 6 target proteins defined in DrugBank for this nutraceutical.
 1 
1 of these target proteins has one or more structures in the PDB.
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Target proteins

DrugBank nutraceutical Target 1:   UniProt id: Q15758 (AAAT_HUMAN)  -  Neutral amino acid transporter B(0)
UniProt id: Q15758    541 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank nutraceutical Target 2:   UniProt id: Q7L266 (ASGL1_HUMAN)  -  ASRGL1 protein
UniProt id: Q7L266    307 a.a.  
1. 4hlo A,B     300 a.a. 298   X-ray 1.95 Å
  2. 4osx A,B     300 a.a. 298   X-ray 1.95 Å
  3. 4gdv A,B     298 a.a. 296   X-ray 1.75 Å
  4. 4pvr A,B     298 a.a. 296   X-ray 1.75 Å
  5. 4o0d A,B     299 a.a. 296   X-ray 1.95 Å
   more ...
There are no PDB entries containing l-asparagine bound to this target protein, although there are 20 entries of the target protein (click the orange, plus icon for a list).
DrugBank nutraceutical Target 3:   UniProt id: Q96I59 (SYNM_HUMAN)  -  Probable asparaginyl-tRNA synthetase, mitochondrial
UniProt id: Q96I59    477 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank nutraceutical Target 4:   UniProt id: Q99624 (S38A3_HUMAN)  -  System N amino acid transporter 1
UniProt id: Q99624    504 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank nutraceutical Target 5:   UniProt id: P08243 (ASNS_HUMAN)  -  Asparagine synthetase [glutamine-hydrolyzing]
UniProt id: P08243    561 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank nutraceutical Target 6:   UniProt id: O43776 (SYNC_HUMAN)  -  Asparaginyl-tRNA synthetase, cytoplasmic
UniProt id: O43776    548 a.a.  
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)

Key:    PfamA domain  PfamB domain  Secondary structure  Bound drug molecule

 

 

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