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DB00130 : l-glutamine

Approved nutraceutical l-glutamine ... 3 targets DB00130

Generic name: l-glutamine
 
Brand name(s): cebrogen, earthlink science glutamine chews chocolate, glavamin, glutamine express, glutamine fuel mega, glutamine fuel powder, l-glutamine power, saforis, stimulina.
Formula: C5H10N2O3
IUPAC Formula: (2s)-2-Amino-4-Carbamoylbutanoic acid

3
There are 3 target proteins defined in DrugBank for this nutraceutical.
 2 
2 of these target proteins have one or more structures in the PDB.
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Target proteins

DrugBank nutraceutical Target 1:   UniProt id: P17812 (PYRG1_HUMAN)  -  CTP synthase 1
UniProt id: P17812    591 a.a.  
1. 2vo1 A,B     235 a.a. 233   X-ray 2.80 Å
  2. 2c5m A,B,D     233 a.a. 231   X-ray 2.80 Å
There are no PDB entries containing l-glutamine bound to this target protein, although there are 2 entries of the target protein (click the orange, plus icon for a list).
DrugBank nutraceutical Target 2:   UniProt id: Q06203 (PUR1_HUMAN)  -  Amidophosphoribosyltransferase
  No Pfam domain assignments available for this protein.
 
There are no structures of the target protein in the PDB (click icon on left for list of closest matches)
DrugBank nutraceutical Target 3:   UniProt id: P15104 (GLNA_HUMAN)  -  Glutamine synthetase
UniProt id: P15104    373 a.a.  
1. 2qc8 A,B,C,D,...     356 a.a. 356   X-ray 2.60 Å
  2. 2ojw A,B,C,D,E     360 a.a. 355   X-ray 2.05 Å
There are no PDB entries containing l-glutamine bound to this target protein, although there are 2 entries of the target protein (click the orange, plus icon for a list).

Key:    PfamA domain  Secondary structure  Bound drug molecule

The black crosses on the secondary structure diagrams indicate where the PDB and UniProt sequences differ.

 

 

Structure selection

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LIGPLOT diagrams
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