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DB00058 : alpha-1-proteinase inhibitor

Approved biotech drug alpha-1-proteinase inhibitor ... 1 target DB00058

Brand name(s): aralast (baxter), prolastin (talecris biotherapeutics c formerly bayer).
UniProt accession: P01009 (A1AT_HUMAN)

1
There is 1 target protein defined in DrugBank for this biotech drug.
 1 
The target protein has one or more structures in the PDB.
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Target proteins

DrugBank biotech drug Target 1:   UniProt id: P08246 (ELNE_HUMAN)  -  Leukocyte elastase
UniProt id: P08246    266 a.a.  
1. 2z7f E     218 a.a. 218   X-ray 1.70 Å
  2. 1ppf E     218 a.a. 218   X-ray 1.80 Å
  3. 4nzl A     218 a.a. 218   X-ray 1.85 Å
  4. 3q76 A,B     218 a.a. 218   X-ray 1.86 Å
  5. 1h1b A,B     218 a.a. 218   X-ray 2.00 Å
   more ...
There are no PDB entries containing alpha-1-proteinase inhibitor bound to this target protein, although there are 10 entries of the target protein (click the orange, plus icon for a list).

Key:    PfamA domain  Secondary structure  Bound drug molecule

 

 

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