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Proteins in SwissProt homologous to 1h3bA

70 proteins with E() < 0.001

Homologs in PDB


Acc   E.C. E() % id alen 45
&E
169
&W
365
&F
376
*D
420
&Y
451
&H
489
&W
495
*Y
601
&F
605
&F
609
&Y
P33247
SQHC_ALIAD
Squalene--hopene cyclase; Squalene--hopa4.2.1.129, 5.4.99.170100.0620 &E&W&F*D&Y&H&W*Y&F&F&Y
B3Y522
DCD_DRYCA
Dammaradiene synthase5.4.99.371.6e-10241.4648 &H&W&F*D&F&R&W*Y&F&F&Y
P54924
SQHC_BRAJA
Squalene--hopene cyclase; Squalene--hopa4.2.1.129, 5.4.99.172.1e-9240.9633 &E&W&F*D&F&R&W*Y&F&F&Y
P33990
SQHC_ZYMMO
Squalene--hopene cyclase; Squalene--hopa4.2.1.129, 5.4.99.172.4e-9239.9626 &E&W&F*D&F&R&W*Y&F&F&Y
P55348
SQHC_RHISN
Probable squalene--hopene cyclase; Squal4.2.1.129, 5.4.99.171.8e-9039.4632 &E&W&F*D&F&R&W*Y&F&F&Y
Q796C3
SQHC_BACSU
Sporulenol synthase; Tetraprenyl-beta-cu4.2.1.1372.2e-6031.4636 &F&Y&F*D&F&R&W*Y&L&F&Y
Q4WR16
PDSA_ASPFU
Protostadienol synthase A5.4.99.321.9e-3826.9650 &R&H&F*D&Y&S&W*Y&P--&Y
B0Y5B4
PDSA_ASPFC
Protostadienol synthase A5.4.99.321.9e-3826.9650 &R&H&F*D&Y&S&W*Y&P--&Y
Q55D85
CAS1_DICDI
Cycloartenol synthase; 2,3-epoxysqualene5.4.99.81.2e-3724.1648 &G&H&F*D&Y&A&W*Y&F&C&Y
A1CVK0
PDSA_NEOFI
Protostadienol synthase A5.4.99.323.4e-3726.6650 &R&H&F*D&Y&S&W*Y&P--&Y
Q6BE23
OXSC_CUCPE
Probable oxidosqualene cyclase2.4e-3626.2682 &G&H&F*D&Y&A&W*Y&F&C&Y
Q8W3Z4
CAS1_BETPL
Cycloartenol synthase5.4.99.84e-3625.7668 &G&H&F*D&Y&A&W*Y&F&C&Y
Q2XPU6
CAS1_RICCO
Cycloartenol synthase; Short=RcCAS5.4.99.86.3e-3626.1670 &G&H&F*D&Y&A&W*Y&F&C&Y
P48449
ERG7_HUMAN
Lanosterol synthase; 2,3-epoxysqualene--5.4.99.78.3e-3626.0643 &G&H&F*D&Y&A&W*Y&F&C&Y
Q6BE25
CAS1_CUCPE
Cycloartenol synthase5.4.99.81.2e-3525.6673 &G&H&F*D&Y&A&W*Y&F&C&Y
H2KWF1
PAKSY_ORYSJ
Parkeol synthase5.4.99.471.4e-3525.5670 &G&Y&F*D&F&S&W*Y&F&A&Y
Q8W3Z2
LUPS_BETPL
Lupeol synthase5.4.99.412.3e-3525.4665 &P&Y&F*D&W&H&W*Y&F&C&Y
P38605
CAS1_ARATH
Cycloartenol synthase; Short=AtCYC; 2,3-5.4.99.83.7e-3525.4668 &G&H&F*D&Y&A&W*Y&F&C&Y
Q8BLN5
ERG7_MOUSE
Lanosterol synthase; 2,3-epoxysqualene--5.4.99.74.8e-3525.1646 &G&H&F*D&Y&A&W*Y&F&C&Y
P48450
ERG7_RAT
Lanosterol synthase; 2,3-epoxysqualene--5.4.99.71.1e-3425.9649 &G&H&F*D&Y&A&W*Y&F&C&Y
A8C981
TARS_RHISY
Taraxerol synthase; Short=RsM25.4.99.351.3e-3426.2663 &P&Y&F*D&A&S&W*Y&L&C&Y
Q6Z2X6
CAS_ORYSJ
Cycloartenol synthase5.4.99.82.1e-3425.1666 &G&H&F*D&Y&A&W*Y&F&C&Y
Q764T8
LUPS_GLYGL
Lupeol synthase; Short=GgLUS15.4.99.416.5e-3424.8669 &A&Y&F*D&W--&W*Y&F&C&Y
Q9SLP9
CAS1_LUFCY
Cycloartenol synthase; Short=LcCAS15.4.99.81.1e-3325.4674 &G&H&F*D&Y&A&W*Y&F&C&Y
P84466
ERG7_BOVIN
Lanosterol synthase; 2,3-epoxysqualene--5.4.99.72.2e-3325.4658 &G&H&F*D&Y&A&W*Y&F&C&Y
E2IUB0
CASS_KALDA
Cycloartenol synthase; Short=KdCAS5.4.99.82.8e-3325.2670 &G&H&F*D&Y&A&W*Y&F&C&Y
Q9SXV6
CAS1_GLYGL
Cycloartenol synthase5.4.99.84.4e-3325.7673 &G&H&F*D&Y&A&W*Y&F&C&Y
O82139
CAS1_PANGI
Cycloartenol Synthase5.4.99.84.4e-3325.2667 &G&H&F*D&Y&A&W*Y&F&C&Y
Q9LVY2
PEN3_ARATH
Tirucalladienol synthase; Pentacyclic tr5.4.99.565.2e-3324.4664 &P&Y&Y*D&W&R&W*Y&Y&V&F
Q8W3Z3
CAS2_BETPL
Cycloartenol synthase 25.4.99.89.8e-3326.1670 &G&H&F*D&Y&A&W*Y&F&C&Y
Q1G1A4
LAS1_ARATH
Lanosterol synthase5.4.99.71.3e-3225.0661 &A&H&F*D&Y&A&W*Y&F&C&Y
E4V6I8
PDSA_ARTGP
Protostadienol synthase A5.4.99.322.9e-3226.4659 --&W&F*D&F&S&W*Y&C--&Y
Q9SYN1
PEN6_ARATH
Seco-amyrin synthase; Alpha-seco-amyrin 5.4.99.52, 5.4.99.543.6e-3225.0673 &P&Y&F*D&W&R&W*Y&F&V&Y
Q9C5M3
LUP1_ARATH
Lupeol synthase 1; Short=AtLUP1; Lupan-34.2.1.128, 5.4.99.416.6e-3223.8665 &P&Y&F*S&W&S&W*Y&F&C&Y
Q948R6
IMFS_LUFCY
Isomultiflorenol synthase; Short=LcIMS15.4.99.369.2e-3225.5678 --&Y&F*S&W&S&W*Y&F&C&F
O23390
BARS1_ARATH
Baruol synthase; Short=AtBARS1; Pentacyc5.4.99.571.3e-3124.9671 &P&Y&F*D&A&Q&W*Y&F&V&F
O82146
BAMS2_PANGI
Beta-Amyrin Synthase 25.4.99.391.3e-3125.0677 &C&Y&F*S&W&M&W*Y&F&C&Y
Q9FZI2
LUP5_ARATH
Lupeol synthase 5; Short=AtLUP51.5e-3125.9667 &P&Y&L*S&W&A&W*Y&M&C&Y
Q9FI37
PEN4_ARATH
Thalianol synthase; Short=AtTHAS1; Penta5.4.99.311.5e-3128.1677 &P&Y&F*D&W&S&W*Y&F&V&F
Q2XPU7
LUPS_RICCO
Lupeol synthase5.4.99.413.9e-3125.0668 &F&Y&F*D&W&L&W*Y&F&C&Y
Q8W3Z1
BAMS_BETPL
Beta-amyrin synthase5.4.99.396.5e-3123.7667 &C&Y&F*D&W&S&W*Y&F&C&Y
B9X0J1
STBOS_STERE
Baccharis oxide synthase; Short=StrBOS5.4.99.517.3e-3125.3665 &C&Y&F*D&W&T&W*Y&F&C&Y
Q6BE24
CUCS_CUCPE
Cucurbitadienol synthase5.4.99.337.4e-3125.6660 &G&H&L*D&Y&A&W*Y&F&C&Y
Q9FJV8
PEN5_ARATH
Marneral synthase; Short=AtMRN1; Pentacy5.4.99.531e-3024.3671 &P&Y&F*D&W&E&W*Y&I&M&Y
E7DN63
BAMS_SOLLC
Beta-amyrin synthase; Triterpenoid synth5.4.99.391e-3024.5665 &C&Y&F*D&W&L&W*Y&F&C&Y
Q9FR95
PEN1_ARATH
Arabidiol synthase; Pentacyclic triterpe4.2.1.1242.3e-3026.9683 &P&Y&F*D&W&H&W*Y&F&V&Y
Q9LRH7
ABAMS_PEA
Mixed-amyrin synthase5.4.99.39, 5.4.99.402.7e-3025.0667 &C&Y&F*S&S&L&W*Y&F&C&Y
Q9LRH8
BAMS_PEA
Beta-amyrin synthase5.4.99.393.1e-3024.8664 &P&Y&F*D&W&L&W*Y&F&C&Y
A8CDT3
LUPS_BRUGY
Lupeol synthase; Short=BgLUS5.4.99.413.6e-3025.6663 &S&Y&F*S&A&L&W*S&F&C&Y
Q9MB42
BAMS_GLYGL
Beta-amyrin synthase5.4.99.393.7e-3024.3662 &C&Y&F*D&W&L&W*Y&F&C&Y
E2IUA6
TARS_KALDA
Taraxerol synthase; Short=KdTAS5.4.99.354.4e-3023.4666 &C&Y&F*D&W&S&W*Y&F&C&Y
E7DN64
DAMS_SOLLC
Delta-amyrin synthase; Alpha-amyrin synt5.4.99.39, 5.4.99.40, 5.4.99.555.9e-3023.9665 &C&Y&F*D&W&S&W*Y&F&C&Y
Q8RWT0
LUP2_ARATH
Amyrin synthase LUP2; Alpha-amyrin synth5.4.99.39, 5.4.99.40, 5.4.99.411.1e-2924.3666 &P&Y&L*S&V&Q&W*Y&F&C&Y
B6EXY6
LUP4_ARATH
Beta-amyrin synthase; Short=AtBAS; Lupeo5.4.99.392.9e-2924.7668 &C&Y&F*S&W&S&W*Y&F&C&Y
Q9LS68
PEN7_ARATH
Putative pentacyclic triterpene synthase2.9e-2923.8671 &P&Y&F*D&W&H&W*Y&Y&V&Y
Q96WJ0
ERG7_PNECA
Lanosterol synthase; 2,3-epoxysqualene--5.4.99.73.7e-2924.2637 &G&H&F*D&Y&A&W*Y&F&C&Y
Q10231
ERG7_SCHPO
Lanosterol synthase; 2,3-epoxysqualene--5.4.99.73.7e-2924.2644 &G&W&W*D&Y&L&W*Y&F&V&Y
A8CDT2
BAS_BRUGY
Beta-amyrin synthase; Short=BgbAS5.4.99.394e-2923.6666 &P&Y&F*D&W&L&W*Y&F&C&Y
A8C980
GERS_RHISY
Germanicol synthase; Short=RsM15.4.99.347.5e-2923.6661 &C&Y&F*D&W&L&W*Y&F&C&Y
P38604
ERG7_YEAST
Lanosterol synthase; 2,3-epoxysqualene--5.4.99.71.2e-2825.8654 &G&W&F*D&Y&L&W*Y&F&C&Y
O82140
BAMS1_PANGI
Beta-Amyrin Synthase 15.4.99.392.3e-2824.1667 &C&Y&F*D&W&L&W*Y&F&C&Y
E2IUA9
LUPS_KALDA
Lupeol synthase; Short=KdLUS5.4.99.419.8e-2823.3669 &C&Y&F*D&A&L&W*Y&F&C&Y
F8WQD0
SHS1_ASTTA
Shionone synthase; Short=AtaSHS5.4.99.461.1e-2724.2670 &Q&Y&F*S&W&L&W*Y&F&C&Y
Q04782
ERG7_CANAL
Lanosterol synthase; 2,3-epoxysqualene--5.4.99.71.7e-2724.1655 &N&H&E*E&F&L&W*Y&F&C&Y
P0C8Y0
LUP3_ARATH
Camelliol C synthase; Lupeol synthase 3;5.4.99.385.7e-2723.3665 &C&Y&F*D&W&L&W*Y&F&C&Y
Q08IT1
DADIS_PANGI
Dammarenediol II synthase4.2.1.1252.4e-2623.4679 &P&Y&F*S&W&S&W*Y&Y&S&Y
Q2R712
ACBSY_ORYSJ
Achilleol B synthase5.4.99.487.3e-2622.6655 &L&F&L*G&Y&S&W*Y&F&L&Y
E2IUA8
FRIES_KALDA
Friedelin synthase; Short=KdFRS5.4.99.508.1e-2523.2669 &C&Y&F*D&W&L&W*Y&F&C&F
E2IUA7
GLUTS_KALDA
Glutinol synthase; Short=KdGLS5.4.99.491.5e-2423.4668 &C&Y&F*D&A&L&W*Y&F&C&F
Q9AJE4
CYC1_KITGR
Terpentedienyl-diphosphate synthase5.5.1.157.6e-0631.3198 ----------&H&W*Y&L--&Y

Proteins identified as mutant are highlighted in maroon. Conservative changes in active site residues, e.g. &K, are marked in green. Non-conservative changes to active site residues (&A) are highlighted in red. Library sequence residues identical to MACie active site residues are shown in grey.

Likewise, E.C. numbers identical to the MACiE protein are shown in grey; differences in black.


Homologs in SwissProt for MACiE ID:


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