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Proteins in SwissProt homologous to 1a41A

7 proteins with E() < 0.001

Homologs in PDB


Acc   E.C. E() % id alen 130
*R
167
*K
223
&R
265
&H
274
*Y
P68697
TOP1_VACCC
DNA topoisomerase 1B; Short=TopIB; DNA t5.99.1.26.7e-9996.5230 *R*K&R&H*Y
Q76ZS7
TOP1_VACCA
DNA topoisomerase 1B; Short=TopIB; DNA t5.99.1.26.7e-9996.5230 *R*K&R&H*Y
P68698
TOP1_VACCW
DNA topoisomerase 1B; Short=TopIB; DNA t5.99.1.26.7e-9996.5230 *R*K&R&H*Y
P32989
TOP1_VAR67
DNA topoisomerase 1; DNA topoisomerase I5.99.1.21.6e-9896.1230 *R*K&R&H*Y
P16472
TOP1_RFVKA
DNA topoisomerase 1; DNA topoisomerase I5.99.1.23.3e-5856.8229 *R*K&R&H*Y
Q7T6X9
TOP1E_MIMIV
DNA topoisomerase 1B; Short=TopIB; DNA t5.99.1.21.3e-0924.2252 *R*K&R&H*Y
Q54RC3
TOP1_DICDI
DNA topoisomerase 1; DNA topoisomerase I5.99.1.20.0006827.7141 *R*K&R----

Proteins identified as mutant are highlighted in maroon. Conservative changes in active site residues, e.g. &K, are marked in green. Non-conservative changes to active site residues (&A) are highlighted in red. Library sequence residues identical to MACie active site residues are shown in grey.

Likewise, E.C. numbers identical to the MACiE protein are shown in grey; differences in black.


Homologs in SwissProt for MACiE ID:


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