spacer

MACiE Entries homologous to 1ni4

MACiE does not contain the PDB code you entered, but MACiE contains the following PDB codes that are homologous to it:


MACiE Entry: 1dtw
EC 1.2.4.4
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
Species: Homo sapiens
Catalytic Residues:  Glu76B  Ser162A  His291A  Ser292A  
CSA Entry: 1ni4
EC 1.2.4.1
pyruvate dehydrogenase (acetyl-transferring)
Species: Homo sapiens
Catalytic Residues:  Glu59B  His128B  His263C  

These enzymes differ only at the serial number level of the EC classification.
It is likely that the mechanisms of these enzymes can be transferred with relative confidence.



MACiE Entry: 1n0h
EC 2.2.1.6
acetolactate synthase
Species: Saccharomyces cerevisiae
Catalytic Residues:  Glu139A  Gln202A  Lys251A  Met582B  
CSA Entry: 1ni4
EC 1.2.4.1
pyruvate dehydrogenase (acetyl-transferring)
Species: Homo sapiens
Catalytic Residues:  Glu59B  His128B  His263C  

Whilst these entries are considered homologous, they differ at the Class level of the EC Classification.
The mechanisms are unlikely to be the same.



MACiE Entry: 1pow
EC 1.2.3.3
pyruvate oxidase
Species: Lactobacillus plantarum
Catalytic Residues:  Glu59B  Phe121A  Gln122A  Val394A  Phe479A  Ile480A  
CSA Entry: 1ni4
EC 1.2.4.1
pyruvate dehydrogenase (acetyl-transferring)
Species: Homo sapiens
Catalytic Residues:  Glu59B  His128B  His263C  

Whilst these entries are considered homologous, they differ at the sub-subclass level of the EC classification.
Their mechanisms may not be the same.



MACiE Entry: 1trk
EC 2.2.1.1
transketolase
Species: Saccharomyces cerevisiae
Catalytic Residues:  His30A  His263A  Glu418B  His481B  
CSA Entry: 1ni4
EC 1.2.4.1
pyruvate dehydrogenase (acetyl-transferring)
Species: Homo sapiens
Catalytic Residues:  Glu59B  His128B  His263C  

Whilst these entries are considered homologous, they differ at the Class level of the EC Classification.
The mechanisms are unlikely to be the same.



MACiE Entry: 1w85
EC 1.2.4.1
pyruvate dehydrogenase (acetyl-transferring)
Species: Geobacillus stearothermophilus
Catalytic Residues:  Glu59B  His128B  Arg267C  His271C  Tyr281C  
CSA Entry: 1ni4
EC 1.2.4.1
pyruvate dehydrogenase (acetyl-transferring)
Species: Homo sapiens
Catalytic Residues:  Glu59B  His128B  His263C  


MACiE Entry: 2pan
EC 4.1.1.47
tartronate-semialdehyde synthase
Species: Escherichia coli
Catalytic Residues:  Val25A  Val51A  Leu421A  Leu476A  Ile479A  
CSA Entry: 1ni4
EC 1.2.4.1
pyruvate dehydrogenase (acetyl-transferring)
Species: Homo sapiens
Catalytic Residues:  Glu59B  His128B  His263C  

Whilst these entries are considered homologous, they differ at the Class level of the EC Classification.
The mechanisms are unlikely to be the same.