MACiE, which stands for Mechanism, Annotation and Classification in Enzymes, is a collaborative project between the Thornton Group at the European Bioinformatics Institute, the Bertini Group at the Magnetic Resonance Center (CERM) in Florence (Italy) with Metal-MACiE and the Mitchell Group at the University of St Andrews.
You might try searching by EC number, enzyme name, CATH code or sequence:
e.g. beta-lactamase, wildcard characters are "%" (for zero or more characters) and "_" (for a single character).
Protein sequence for similarity search against MACiE:
Last Updated: 6th September 2011