Entry M0291 22.214.171.124 malonyl-CoA-acyl carrier protein transacylase
Ser92 is activated towards nucleophilic attack at the thio-carbonyl of malonyl-CoA by the general base His201.
Comment: A catalytic dyad is present between Ser92A and His201A, with the protonated form of His201A being stabilised through a hydrogen bond with the main chain carbonyl of Gln250A .
Amino acids involved in the reaction step.
||Bonds Changed in Order
||Atom Types Involved
The C-O bond changes from a double to single bond
View similar reactions in MACiE.