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Entry M0259    5.5.1.8    bornyl diphosphate synthase

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Step 02

The diphosphate initiates nucleophilic attack at the C4 carbon, which causes double bond rearrangement and the formation of the linalyl diphosphate intermediate.

GIF of Reaction Step M0259.stg02



Mechanisms

Bimolecular Nucleophilic Addition

Mechanism Components

Bond Formation
Bond Order Change
Intermediate Formation

Amino acids involved in the reaction step.

Amino Acid Location of Function Activity Function
Phe578 Side Chain spectator Steric Role
van der Waals interaction
Trp323 Side Chain spectator Steric Role
van der Waals interaction
Val452 Side Chain spectator Steric Role
van der Waals interaction
Ile344 Side Chain spectator Steric Role
van der Waals interaction

Metal Cofactors involved in Step 02

Metal Type Metal Identity Chain Activity Function
magnesium MG 701 A spectator Substrate Binding
Electrostatic Stabiliser
magnesium MG 702 A spectator Substrate Binding
Electrostatic Stabiliser
magnesium MG 703 A spectator Substrate Binding
Electrostatic Stabiliser

Reactive Centre

Bonds Formed Bonds Cleaved Bonds Changed in Order Atom Types Involved
C-O
None
The C-C bond changes from a single to double bond
The C-C bond changes from a double to single bond
C
O

View similar reactions in MACiE.


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