Entry M0238 188.8.131.52 assemblin
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His63 deprotonates water, which can then act as the nucleophile for attack on the carbonyl carbon of the acyl-enzyme. This forms a tetrahedral intermediate that is stabilised by the oxyanion hole.
Amino acids involved in the reaction step.
||Bonds Changed in Order
||Atom Types Involved
The C-O bond changes from a double to single bond
View similar reactions in MACiE.