Entry M0236 220.127.116.11 3-dehydro-L-gulonate-6-phosphate decarboxylase
The substrate decarboxylates to form the 1,2-cis-enediolate intermediate and carbon dioxide.
This reaction is irreversible.
Comment: It has been suggested that the ground state is destabilised due to the interactions between the hydrophobic pocket and the negatively-charged carboxylate of 3-dehydro-L-gulonate 6-phosphate.
Amino acids involved in the reaction step.
Metal Cofactors involved in Step 01
||Bonds Changed in Order
||Atom Types Involved
The C-C bond changes from a single to double bond
The C-O bond changes from a single to double bond
The C-O bond changes from a double to single bond
View similar reactions in MACiE.