Entry M0223 22.214.171.124 pyruvate carboxylase
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Reaction occurs in the CT domain. The Asp549 deprotonates pyruvate, activating the pyruvate in a keto-enol tautomerisation.
Comment: This step occurs in the Carboxyl Transferase (CT) domain.
Amino acids involved in the reaction step.
Organic Cofactors involved in the reaction step
Metal Cofactors involved in Step 05
||Bonds Changed in Order
||Atom Types Involved
The C-C bond changes from a single to double bond
The C-O bond changes from a double to single bond
View similar reactions in MACiE.