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Entry M0156    2.8.4.1    coenzyme-B sulfoethylthiotransferase

Previous Step

Step 05

The thiyl radical of coenzyme M donates a second electron to the nickel of factor 430, regenerating the Ni(I) oxidation state.

GIF of Reaction Step M0156.stg05



Mechanisms

Electron Transfer
Radical Termination

Mechanism Components

Overall Product Formed
Cofactor Regenerated
Intermediate Terminated
Enzyme Regenerated

Amino acids involved in the reaction step.

Amino Acid Location of Function Activity Function
Tyr367E Side Chain spectator Electrostatic Stabiliser
Gln147 Side Chain spectator Electrostatic Stabiliser
Metal Ligand

Organic Cofactors involved in the reaction step

Cofactor Type Cofactor Activity Function
Coenzyme B TP79000 reactant Covalently Attached
Hydrogen Bond Acceptor
Coenzyme M COM9700 reactant Covalently Attached
One Electron Donor

Metal Cofactors involved in Step 05

Metal Type Metal Identity Chain Activity Function
nickel F43 700 x reactant One Electron Acceptor

Reactive Centre

Bonds Formed Bonds Cleaved Bonds Changed in Order Atom Types Involved
None
None
None
None

View similar reactions in MACiE.


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