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Entry M0146    1.97.1.2    pyrogallol hydroxytransferase

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Step 03

Tyr404 deprotonates the second substrate (1,2,3,5-tetrahydroxybenzene) at the C2-OH position.

GIF of Reaction Step M0146.stg03



Mechanisms

Proton Transfer

Mechanism Components

Overall Reactant Used
Bond Formation
Bond Cleavage
Intermediate Formation

Amino acids involved in the reaction step.

Amino Acid Location of Function Activity Function
His144 Side Chain spectator Hydrogen Bond Donor
Asp174 Side Chain spectator Hydrogen Bond Donor
Tyr404 Side Chain reactant Hydrogen Bond Acceptor
Proton Acceptor

Metal Cofactors involved in Step 03

Metal Type Metal Identity Chain Activity Function
molybdenum 4MO 902 A spectator Substrate Binding

Reactive Centre

Bonds Formed Bonds Cleaved Bonds Changed in Order Atom Types Involved
O-H
O-H
None
H
O

View similar reactions in MACiE.


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