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Entry M0107    1.2.99.2    carbon-monoxide dehydrogenase (acceptor)

Previous Step

Step 08

Water deprotonates Glu763 in an inferred return step.

This reaction step has been inferred

GIF of Reaction Step M0107.stg08



Mechanisms

Proton Transfer

Mechanism Components

Bond Formation
Bond Cleavage
Enzyme Regenerated

Amino acids involved in the reaction step.

Amino Acid Location of Function Activity Function
Glu763 Side Chain reactant Hydrogen Bond Donor
Proton Donor
Cys388 Side Chain spectator Metal Ligand
Electrostatic Stabiliser

Organic Cofactors involved in the reaction step

Cofactor Type Cofactor Activity Function
FAD FAD3932 spectator Not Active

Metal Cofactors involved in Step 08

Metal Type Metal Identity Chain Activity Function
iron FES 3907 x spectator Not Active
iron FES 3908 x spectator Not Active
copper CUB 3921 x spectator Not Active
molybdenum CUB 3921 x spectator Substrate Binding

Reactive Centre

Bonds Formed Bonds Cleaved Bonds Changed in Order Atom Types Involved
O-H
O-H
None
H
O

View similar reactions in MACiE.


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