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Entry M0103    1.1.3.38    vanillyl-alcohol oxidase

Next Step

Step 01

Asp170 deprotonates the 4-OH of the substrate, forming a pheonlate.

GIF of Reaction Step M0103.stg01



Mechanisms

Proton Transfer

Mechanism Components

Overall Reactant Used
Bond Formation
Bond Cleavage
Intermediate Formation

Amino acids involved in the reaction step.

Amino Acid Location of Function Activity Function
Arg504 Side Chain spectator Hydrogen Bond Donor
Tyr503 Side Chain spectator Hydrogen Bond Donor
Tyr108 Side Chain spectator Hydrogen Bond Donor
Asp170 Side Chain reactant Hydrogen Bond Acceptor
Proton Acceptor
His422 Side Chain spectator Covalently Attached

Organic Cofactors involved in the reaction step

Cofactor Type Cofactor Activity Function
FAD FAD600 spectator Hydrogen Bond Acceptor
Hydrogen Bond Donor
Covalently Attached

Reactive Centre

Bonds Formed Bonds Cleaved Bonds Changed in Order Atom Types Involved
O-H
O-H
None
H
O

View similar reactions in MACiE.


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