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Entry M0096    3.5.3.3    creatinase

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Step 02

The methylated nitrogen of the guanidinium group deprotonates His232.

GIF of Reaction Step M0096.stg02



Mechanisms

Proton Transfer

Mechanism Components

Bond Formation
Bond Cleavage
Intermediate Formation

Amino acids involved in the reaction step.

Amino Acid Location of Function Activity Function
Glu358 Side Chain spectator Hydrogen Bond Acceptor
His232 Side Chain reactant Proton Donor
Hydrogen Bond Donor
Glu262 Side Chain spectator Hydrogen Bond Acceptor

Reactive Centre

Bonds Formed Bonds Cleaved Bonds Changed in Order Atom Types Involved
N-H
N-H
None
H
N

View similar reactions in MACiE.


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