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Entry M0089    4.2.3.7    pentalenene synthase

Previous Step

Step 07

Water deprotonates His309 in an inferred step to regenerate the enzyme active site.

This reaction step has been inferred

GIF of Reaction Step M0089.stg07



Mechanisms

Proton Transfer

Mechanism Components

Bond Cleavage
Bond Formation
Enzyme Regenerated

Amino acids involved in the reaction step.

Amino Acid Location of Function Activity Function
His309 Side Chain reactant Proton Donor
Hydrogen Bond Donor
Phe76 Side Chain spectator van der Waals interaction
Phe77 Side Chain spectator van der Waals interaction
Asn219 Side Chain spectator Not Active
Trp308 Side Chain spectator van der Waals interaction

Metal Cofactors involved in Step 07

Metal Type Metal Identity Chain Activity Function
magnesium MG(not in PDB) 1 x spectator Not Active

Reactive Centre

Bonds Formed Bonds Cleaved Bonds Changed in Order Atom Types Involved
O-H
N-H
None
H
N
O

View similar reactions in MACiE.


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