Entry M0065 220.127.116.11 adenylosuccinate synthase
Asp13 deprotonates IMP with concomitant tautomerisation to give the oxyanion, which is stabilised by a hydrogen bond from Gln224. Activated IMP is produced. His41 and Mg stabilise the GTP.
Amino acids involved in the reaction step.
Metal Cofactors involved in Step 01
||Bonds Changed in Order
||Atom Types Involved
The C-N bond changes from a single to double bond
The C-O bond changes from a double to single bond
View similar reactions in MACiE.