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Entry M0060    3.5.99.6    glucosamine-6-phosphate deaminase

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Step 03

The newly formed oxyanion deprotonates Asp72.

GIF of Reaction Step M0060.stg03



Mechanisms

Proton Transfer

Mechanism Components

Bond Cleavage
Bond Formation
Intermediate Formation

Amino acids involved in the reaction step.

Amino Acid Location of Function Activity Function
His143 Side Chain spectator Hydrogen Bond Acceptor
Hydrogen Bond Donor
Asp72 Side Chain reactant Proton Donor
Hydrogen Bond Donor
Glu148 Side Chain spectator Hydrogen Bond Acceptor
Asp141 Side Chain spectator Hydrogen Bond Acceptor

Reactive Centre

Bonds Formed Bonds Cleaved Bonds Changed in Order Atom Types Involved
O-H
O-H
None
H
O

View similar reactions in MACiE.


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