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Entry M0049    4.1.1.22    histidine decarboxylase

Previous Step

Step 07

Glu197F deprotonates water in an inferred step.

This reaction step has been inferred

GIF of Reaction Step M0049.stg07



Mechanisms

Proton Transfer

Mechanism Components

Bond Cleavage
Bond Formation
Enzyme Regenerated

Amino acids involved in the reaction step.

Amino Acid Location of Function Activity Function
Tyr62 Side Chain spectator Hydrogen Bond Donor
Glu66 Side Chain spectator Hydrogen Bond Acceptor
Ser81E Main Chain C Terminus spectator Hydrogen Bond Acceptor
Glu197F Side Chain reactant Proton Acceptor
Hydrogen Bond Acceptor
Phe195F Main Chain Amide spectator Hydrogen Bond Donor
Pvl82F Post-Translationally Modified Residue spectator Hydrogen Bond Acceptor

Reactive Centre

Bonds Formed Bonds Cleaved Bonds Changed in Order Atom Types Involved
O-H
O-H
None
H
O

View similar reactions in MACiE.


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