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Entry M0030    2.3.1.54    formate C-acetyltransferase

Previous Step

Step 07

Cys419 abstracts a hydrogen from Gly734, regenerating the glycyl radical ground state.

GIF of Reaction Step M0030.stg07



Mechanisms

Hydrogen Transfer
Radical Propagation

Mechanism Components

Bond Cleavage
Bond Formation
Enzyme Regenerated

Amino acids involved in the reaction step.

Amino Acid Location of Function Activity Function
Cys419 Side Chain reactant Hydrogen Acceptor
Hydrogen Bond Acceptor
Trp333 Side Chain spectator Radical Stabiliser
Hydrogen Bond Donor
Gly734 Main Chain Alpha Carbon reactant Hydrogen Donor
Hydrogen Bond Donor
Cys418 Side Chain spectator Hydrogen Bond Donor

Reactive Centre

Bonds Formed Bonds Cleaved Bonds Changed in Order Atom Types Involved
S-H
C-H
None
C
H
S

View similar reactions in MACiE.


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