Version History for M0132
Version 2.0 => Created
Version 2.1 => Formation of the 4a-hydroperoxy-FMNH is depicted now in 2 steps rather than 3, i.e. the proton transfer of step 3 has been added into step 1. Step 5 has been split into two steps. homolysis of the O-O bond and electron transfer plus a second step for the proton transfer from the intermediate to the His44. Added His45 as a catalytic residue that stabilises the formation of the first two intermediates of the reaction (PMID. 10194361).
Version 2.4 => Step 7 was incorrectly annotated as returning the enzyme to its native state. However, the mechanism utilises an unidentified base, so this cannot be certain and thus has been removed.