Version History for M0065

Annotators:Gemma L. Holliday
Gail J. Bartlett
Daniel E. Almonacid
Date last updated:16/08/2010

Version 1.0 => Created

Version 1.1 => Added a water as a proton relay medium into the inferred return step.

Version 2.5 => The overall reaction was unbalanced at the proton level. This has now been fixed. Further, Lys16 has been added as a catalytic residue. Evidence suggests that, whilst not essential, it may be involved in stabilising the intermediates of the first half-reaction (the phosphoryl transfer) as it is hydrogen bonded to the gamma-phosphate of the GDP substrate. We have also added reference PMID:9115248.