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Structural Information for 1h3b

The following displays the crystal structure (as found in 1h3b, the primary PDB code for the entry) with each catalytic domain highlighted. The catalytic residues are also highlighed in teal and shown in wireframe depiction. Domains which are not classified as catalytic are shown in grey.

This enzyme has 12 catalytic sites (as determined by the Catalytic Site Atlas), only one of which is shown highlighed by CATH domain.
Site 1 covers chain A.
Site 2 covers chain B.
Site 3 covers chain C.
Site 4 covers chain A.
Site 5 covers chain A.
Site 6 covers chain B.
Site 7 covers chain B.
Site 8 covers chain C.
Site 9 covers chain C.
Site 10 covers chain A.
Site 11 covers chain B.
Site 12 covers chain C.


The Catalytic Domains:

The Catalytic Residues

The following shows the catalytic residues (the catalytic residue in focus is labelled in red) and the residues which are donating hydrogen bonds (labelled in blue) and accepting hydrogen bonds (labelled in green).

Asp 376 A

Residues Contacting Asp376A

B Factor
(normalised)
Relative Solvent Accessibility Number of H-Bond Donors Number of H-Bond Acceptors
28.3575
(0.7333)
47.8 5 0

His 451 A

Residues Contacting His451A

B Factor
(normalised)
Relative Solvent Accessibility Number of H-Bond Donors Number of H-Bond Acceptors
14.89
(0.1618)
3.4 2 4

Tyr 495 A

Residues Contacting Tyr495A

B Factor
(normalised)
Relative Solvent Accessibility Number of H-Bond Donors Number of H-Bond Acceptors
15.9025
(0.4823)
8.3 3 2

Phe 365 A

Residues Contacting Phe365A

B Factor
(normalised)
Relative Solvent Accessibility Number of H-Bond Donors Number of H-Bond Acceptors
6.0209
(0.1109)
1.7 1 2

Tyr 420 A

Residues Contacting Tyr420A

B Factor
(normalised)
Relative Solvent Accessibility Number of H-Bond Donors Number of H-Bond Acceptors
36.3483
(0.741)
3.6 3 2

Trp 489 A

Residues Contacting Trp489A

B Factor
(normalised)
Relative Solvent Accessibility Number of H-Bond Donors Number of H-Bond Acceptors
41.6571
(0.3774)
21.3 3 1

Tyr 609 A

Residues Contacting Tyr609A

B Factor
(normalised)
Relative Solvent Accessibility Number of H-Bond Donors Number of H-Bond Acceptors
38.9733
(0.3193)
9.7 3 1

Phe 601 A

Residues Contacting Phe601A

B Factor
(normalised)
Relative Solvent Accessibility Number of H-Bond Donors Number of H-Bond Acceptors
41.0181
(0.4982)
36.8 3 1

Phe 605 A

Residues Contacting Phe605A

B Factor
(normalised)
Relative Solvent Accessibility Number of H-Bond Donors Number of H-Bond Acceptors
42.83
(0.3983)
15.5 3 1

Trp 169 A

Residues Contacting Trp169A

B Factor
(normalised)
Relative Solvent Accessibility Number of H-Bond Donors Number of H-Bond Acceptors
14.6992
(0.151)
1.2 1 1

Glu 45 A

Residues Contacting Glu45A

B Factor
(normalised)
Relative Solvent Accessibility Number of H-Bond Donors Number of H-Bond Acceptors
43.8022
(0.9847)
61.1 5 1

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