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SF4 424 L

Metal-MACiE entry for SF4 424 L

This is a Fe-S cluster termed the F-cluster. All enzymes contain two or more F-clusters. The F clusters serve to transfer electrons between the H cluster and the external electron carrier (cytochrome C3 or cytochrome C6) (PMID2173950).


Metal in MACiE Physiological Metal Site Type
iron iron Fe4S4

Resting State

nativeState of SF4 424 L
Download the coordinates file
Representative Structure
PDB code 1hfe
MACiE Metal Type
(Identity)
iron
(SF4424L)
PDB Metal Type (Identity) iron
(FE1,FE2,FE3,FE4424L)
Oxidation State 2
Coordination Geometry
(Number of ligands)
tetrahedral
(4)

First Coordination Sphere

Ligand Type Ligand (PDB) Ligand (MACiE) Catalytic Binding Mode Contacting Atoms
Amino Acid Residue CYS 179 LCYS 179 L No monodentate SG
Note: It coordinates FE1
Amino Acid Residue CYS 234 LCYS 234 L No monodentate SG
Note: It coordinates FE4
Amino Acid Residue CYS 378 LCYS 378 L No monodentate SG
Note: It coordinates FE3
Amino Acid Residue CYS 382 LCYS 382 L No monodentate SG
Note: It coordinates FE2
Cofactor FS4 424 LFS4 424 L No monodentate S1
Cofactor FS4 424 LFS4 424 L No monodentate S2
Cofactor FS4 424 LFS4 424 L No monodentate S3
Cofactor FS4 424 LFS4 424 L No monodentate S4

Step 01

Metal Functions

This metal is not active in this step.

Structural Information


MACiE Metal Type
(Identity)
iron
(SF4424L)
Oxidation State 2
Coordination Geometry
(Number of ligands)
tetrahedral
(4)

This step has no available structures in the PDB: all the coordinating information are derived from the reaction model in MACiE.





Right Arrow
MACiE Metal Type
(Identity)
iron
(SF4424L)
Oxidation State 2
Coordination Geometry
(Number of ligands)
tetrahedral
(4)

This step has no available structures in the PDB: all the coordinating information are derived from the reaction model in MACiE.


Step 02

Metal Functions

This metal is not active in this step.

Structural Information


MACiE Metal Type
(Identity)
iron
(SF4424L)
Oxidation State 2
Coordination Geometry
(Number of ligands)
tetrahedral
(4)

This step has no available structures in the PDB: all the coordinating information are derived from the reaction model in MACiE.





Right Arrow
MACiE Metal Type
(Identity)
iron
(SF4424L)
Oxidation State 2
Coordination Geometry
(Number of ligands)
tetrahedral
(4)

This step has no available structures in the PDB: all the coordinating information are derived from the reaction model in MACiE.


Step 03

Metal Functions

This metal is not active in this step.

Structural Information


MACiE Metal Type
(Identity)
iron
(SF4424L)
Oxidation State 2
Coordination Geometry
(Number of ligands)
tetrahedral
(4)

This step has no available structures in the PDB: all the coordinating information are derived from the reaction model in MACiE.





Right Arrow
MACiE Metal Type
(Identity)
iron
(SF4424L)
Oxidation State 2
Coordination Geometry
(Number of ligands)
tetrahedral
(4)

This step has no available structures in the PDB: all the coordinating information are derived from the reaction model in MACiE.


Step 04

Metal Functions

Electron Relay

One Electron Acceptor. Note: The electron is provided by a cytochrome C3 or a cytochrome C6.

One Electron Donor. Note: The electron is provided to the an iron-sulfur cluster (FS4_423).

Structural Information


MACiE Metal Type
(Identity)
iron
(SF4424L)
Oxidation State 2
Coordination Geometry
(Number of ligands)
tetrahedral
(4)

This step has no available structures in the PDB: all the coordinating information are derived from the reaction model in MACiE.





Right Arrow
MACiE Metal Type
(Identity)
iron
(SF4424L)
Oxidation State 2
Coordination Geometry
(Number of ligands)
tetrahedral
(4)

This step has no available structures in the PDB: all the coordinating information are derived from the reaction model in MACiE.


Step 05

Metal Functions

This metal is not active in this step.

Structural Information


MACiE Metal Type
(Identity)
iron
(SF4424L)
Oxidation State 2
Coordination Geometry
(Number of ligands)
tetrahedral
(4)

This step has no available structures in the PDB: all the coordinating information are derived from the reaction model in MACiE.





Right Arrow
MACiE Metal Type
(Identity)
iron
(SF4424L)
Oxidation State 2
Coordination Geometry
(Number of ligands)
tetrahedral
(4)

This step has no available structures in the PDB: all the coordinating information are derived from the reaction model in MACiE.


Step 06

Metal Functions

Electron Relay

One Electron Acceptor. Note: The electron is provided by a cytochrome C3 or a cytochrome C6.

One Electron Donor. Note: The electron is provided to the an iron-sulfur cluster (FS4_423).

Structural Information


MACiE Metal Type
(Identity)
iron
(SF4424L)
Oxidation State 2
Coordination Geometry
(Number of ligands)
tetrahedral
(4)

This step has no available structures in the PDB: all the coordinating information are derived from the reaction model in MACiE.





Right Arrow
MACiE Metal Type
(Identity)
iron
(SF4424L)
Oxidation State 2
Coordination Geometry
(Number of ligands)
tetrahedral
(4)

This step has no available structures in the PDB: all the coordinating information are derived from the reaction model in MACiE.



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