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MG(not in PDB) 1 x

Metal-MACiE entry for MG(not in PDB) 1 x

It has been proposed that the enzyme could bind two magnesium ions using a two metal ion hydrolytic mechanism (PMID9000637). On the basis of the proposed model the ion(s) should be involved in substrate binding and stabilize intermediates (PMID9000637).


Metal in MACiE Physiological Metal Site Type
magnesium magnesium mononuclear

Resting State

There is no PDB code associated with this metal atom in the enzyme's resiting state.

MACiE Metal Type
(Identity)
magnesium
(MG(not in PDB)1x)
Oxidation State 2
Coordination Geometry
(Number of ligands)
unknownGeometry
(9999)

This step has no available structures in the PDB: all the coordinating information are derived from the reaction model in MACiE.


Step 01

Metal Functions

Substrate Binding

Electrostatic Stabiliser

Increase Electrophilicity. Note: it increases electrophilicity of substrate

Activator. Note: it polarizes the P-O bond

Structural Information


MACiE Metal Type
(Identity)
magnesium
(MG(not in PDB)1x)
Oxidation State 2
Coordination Geometry
(Number of ligands)
unknownGeometry
(9999)

This step has no available structures in the PDB: all the coordinating information are derived from the reaction model in MACiE.





Right Arrow
MACiE Metal Type
(Identity)
magnesium
(MG(not in PDB)1x)
Oxidation State 2
Coordination Geometry
(Number of ligands)
unknownGeometry
(9999)

This step has no available structures in the PDB: all the coordinating information are derived from the reaction model in MACiE.


Step 02

Metal Functions

This metal is not active in this step.

Structural Information


MACiE Metal Type
(Identity)
magnesium
(MG(not in PDB)1x)
Oxidation State 2
Coordination Geometry
(Number of ligands)
unknownGeometry
(9999)

This is an inferred step.

This step has no available structures in the PDB: all the coordinating information are derived from the reaction model in MACiE.





Right Arrow
MACiE Metal Type
(Identity)
magnesium
(MG(not in PDB)1x)
Oxidation State 2
Coordination Geometry
(Number of ligands)
unknownGeometry
(9999)

This step has no available structures in the PDB: all the coordinating information are derived from the reaction model in MACiE.



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