The enzyme catalyzes the reduction of Hg(2+) to Hg(0) as a means of detoxification (PMID16114877).
|Residue in MACiE*||Atom in MACiE*||Residue Type in MACiE||Physiological
|none||none||mercury||mercury||mononuclear|| Electron pair acceptor|
*It refers to the MACiE reference pdb: 1zk7
|Metal/s Properties in Resting State|
|none||Resting state enzyme (-)|
|-Patel B, Dong A, Fiedler D, Falkowski M, Zelikova J, Summers AO, Pai EF, Miller SM|
NmerA, the metal binding domain of mercuric ion reductase, removes Hg2+ from proteins, delivers it to the catalytic core, and protects cells under glutathione-depleted conditions.
Biochemistry. 2005 Aug 30;44(34):11402-16.(MEDLINE:16114877)
|- Some information have been also deduced from the MACiE mechanism model|