The enzyme catalyzes the hydrolysis of cerebroside 3-sulfate producing cerebroside and sulfate. It uses a divalent cation to perform the catalytic mechanism (PMID11124905).
|Residue in MACiE*||Atom in MACiE*||Residue Type in MACiE||Physiological
|MG 44 x||MG||magnesium||divalent cation||mononuclear|| Coordinates substrate|
*It refers to the MACiE reference pdb: 1auk
|Metal/s Properties in Resting State|
|MG 44 x||Resting state enzyme (1e1z)|
|-von Bülow R, Schmidt B, Dierks T, von Figura K, Usón I|
Crystal structure of an enzyme-substrate complex provides insight into the interaction between human arylsulfatase A and its substrates during catalysis.
J Mol Biol. 2001 Jan 12;305(2):269-77.(MEDLINE:11124905)
|- Some information have been also deduced from the MACiE mechanism model|