CATALYTIC METAL(S)

Metal/Site Information
Residue in MACiE* Atom in MACiE* Residue Type in MACiE Physiological
Metal
Site
Type
Function(s)
MG 161 xMG magnesium magnesium mononuclear Coordinates substrate
Increases electrophilicity
Electrostatic stabiliser
MG 162 xMG magnesium magnesium mononuclear Coordinates substrate
Increases electrophilicity
Electrostatic stabiliser

*It refers to the MACiE reference pdb: 1q0n

Metal/s Properties in Resting State
MG 161 x
Oxidation State 2
Coordination Geometry squarePyramidal
Coordination Number 5
Notes -
MG 162 x
Oxidation State 2
Coordination Geometry octahedral
Coordination Number 6
Notes -


References
-Blaszczyk J, Shi G, Yan H, Ji X
Catalytic center assembly of HPPK as revealed by the crystal structure of a ternary complex at 1.25 A resolution.
Structure. 2000 Oct 15;8(10):1049-58.(MEDLINE:11080626)