The enzyme catalyzes the oxidation of L-lactate to pyruvate. It uses a heme-b2 and FMN to perform the catalysis (PMID11559361).
|Residue in MACiE*||Atom in MACiE*||Residue Type in MACiE||Physiological
|HEM 560 A||FE||iron||iron||haem|| One electron acceptor|
One electron donor
*It refers to the MACiE reference pdb: 1fcb
|Metal/s Properties in Resting State|
|HEM 560 A||Resting state enzyme (1ltd)|
|-Mowat CG, Wehenkel A, Green AJ, Walkinshaw MD, Reid GA, Chapman SK|
Altered substrate specificity in flavocytochrome b2: structural insights into the mechanism of L-lactate dehydrogenation.
Biochemistry. 2004 Jul 27;43(29):9519-26.(MEDLINE:15260495)
|- Some information have been also deduced from the MACiE mechanism model|