CATALYTIC METAL(S)

Metal/Site Information
Residue in MACiE* Atom in MACiE* Residue Type in MACiE Physiological
Metal
Site
Type
Function(s)
MG 435 AMG magnesium magnesium mononuclear Coordinates substrate
Electrostatic stabiliser
Increases acidity
Increases electrophilicity

*It refers to the MACiE reference pdb: 1gim

Metal/s Properties in Resting State
MG 435 A
Oxidation State 2
Coordination Geometry unknownGeometry
Coordination Number unknown
Notes -


References
-Poland BW, Bruns C, Fromm HJ, Honzatko RB
Entrapment of 6-thiophosphoryl-IMP in the active site of crystalline adenylosuccinate synthetase from Escherichia coli.
J Biol Chem. 1997 Jun 13;272(24):15200-5.(MEDLINE:9182542)
- Some information have been also deduced from the MACiE mechanism model