CATALYTIC METAL(S)

Metal/Site Information
Residue in MACiE* Atom in MACiE* Residue Type in MACiE Physiological
Metal
Site
Type
Function(s)
MG 3001 AMG magnesium divalent cation mononuclear Coordinates substrate
Increases electrophilicity
Electrostatic stabiliser

*It refers to the MACiE reference pdb: 1d8c

Metal/s Properties in Resting State
MG 3001 A
Oxidation State 2
Coordination Geometry octahedral
Coordination Number 6
Notes -


References
-Smith CV, Huang CC, Miczak A, Russell DG, Sacchettini JC, Höner zu Bentrup K
Biochemical and structural studies of malate synthase from Mycobacterium tuberculosis.
J Biol Chem. 2003 Jan 17;278(3):1735-43. Epub 2002 Oct 21.(MEDLINE:12393860)
-Howard BR, Endrizzi JA, Remington SJ
Crystal structure of Escherichia coli malate synthase G complexed with magnesium and glyoxylate at 2.0 A resolution: mechanistic implications.
Biochemistry. 2000 Mar 21;39(11):3156-68.(MEDLINE:10715138)
- Some information have been also deduced from the MACiE mechanism model