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Search The CSA
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Catalytic Site Atlas

CSA LITERATURE entry for 2plc

E.C. namephosphatidylinositol diacylglycerol-lyase
SpeciesListeria monocytogenes (strain F2365)
E.C. Number (IntEnz) 4.6.1.13
CSA Homologues of 2plcThere are 10 Homologs
CSA Entries With UniProtID P34024
CSA Entries With EC Number 4.6.1.13
PDBe Entry 2plc
PDBSum Entry 2plc
MACiE Entry 2plc

Literature Report

Introduction
Mechansim
Reaction

Catalytic Sites for 2plc

Annotated By Reference To The Literature - Site 1 (Perform Site Search)
ResidueChainNumberUniProtKB NumberFunctional PartFunctionTargetDescription
AspA278300macie:sideChain
ArgA84106macie:sideChain
AspA4668macie:sideChain
HisA4567macie:sideChain
HisA93115macie:sideChain

Literature References

Notes:
Essen LO
Structural mapping of the catalytic mechanism for a mammalian phosphoinositide-specific phospholipase C.
Biochemistry 1997 36 1704-1718
PubMed: 9048554
Moser J
Crystal structure of the phosphatidylinositol-specific phospholipase C from the human pathogen Listeria monocytogenes.
J Mol Biol 1997 273 269-282
PubMed: 9367761
Heinz DW
Structural and mechanistic comparison of prokaryotic and eukaryotic phosphoinositide-specific phospholipases C.
J Mol Biol 1998 275 635-650
PubMed: 9466937
Hondal RJ
Mechanism of phosphatidylinositol-specific phospholipase C: a unified view of the mechanism of catalysis.
Biochemistry 1998 37 4568-4580
PubMed: 9521777
Katan M.
Families of phosphoinositide-specific phospholipase C: structure and function.
Biochim Biophys Acta 1998 1436 5-17
PubMed: 9838022
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