spacer
View the latest EBI news stories and important announcements...
more

spacer
Search The CSA
PDB ID
UNIPROT ID
EC Number

Catalytic Site Atlas

CSA LITERATURE entry for 1dve

E.C. nameheme oxygenase
SpeciesRattus norvegicus (Rat)
E.C. Number (IntEnz) 1.14.99.3
CSA Homologues of 1dveThere are 43 Homologs
CSA Entries With UniProtID P06762
CSA Entries With EC Number 1.14.99.3
PDBe Entry 1dve
PDBSum Entry 1dve
MACiE Entry 1dve

Literature Report

Introduction
Mechansim
Reaction

Catalytic Sites for 1dve

Annotated By Reference To The Literature - Site 2 (Perform Site Search)
ResidueChainNumberUniProtKB NumberFunctional PartFunctionTargetDescription
ArgA136136macie:sideChain
ArgA136136macie:mainChainCarbonyl
TyrA5858macie:sideChain
ThrA135135macie:mainChainCarbonyl
AspA140140macie:sideChain
GlyA143143macie:mainChainAmide
HisA2525macie:sideChain
GlyA139139macie:mainChainCarbonyl

Literature References

Notes:
Fujii H
A role for highly conserved carboxylate, aspartate-140, in oxygen activation and heme degradation by heme oxygenase-1.
J Am Chem Soc 2001 123 6475-6484
PubMed: 11439033
Li Y
Solution NMR characterization of an unusual distal H-bond network in the active site of the cyanide-inhibited, human heme oxygenase complex of the symmetric substrate, 2,4-dimethyldeuterohemin.
J Biol Chem 2002 277 33018-33031
PubMed: 12070167
Sugishima M
Crystal structure of rat heme oxygenase-1 in complex with heme bound to azide. Implication for regiospecific hydroxylation of heme at the alpha-meso carbon.
J Biol Chem 2002 277 45086-45090
PubMed: 12235152
spacer
spacer