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Search The CSA
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Catalytic Site Atlas

CSA LITERATURE entry for 1bd0

E.C. namealanine racemase
SpeciesBacillus stearothermophilus (Bacteria)
E.C. Number (IntEnz) 5.1.1.1
CSA Homologues of 1bd0There are 53 Homologs
CSA Entries With UniProtID P10724
CSA Entries With EC Number 5.1.1.1
PDBe Entry 1bd0
PDBSum Entry 1bd0
MACiE Entry M0213

Literature Report

Introduction
Mechansim
Reaction

Catalytic Sites for 1bd0

Annotated By Reference To The Literature - Site 1 (Perform Site Search)
ResidueChainNumberUniProtKB NumberFunctional PartFunctionTargetDescription
ArgA136136macie:sideChain
LysA3939macie:sideChain
CysB311311macie:sideChain
TyrB265265macie:sideChain

Annotated By Reference To The Literature - Site 2 (Perform Site Search)
ResidueChainNumberUniProtKB NumberFunctional PartFunctionTargetDescription
CysA311311macie:sideChain
TyrA265265macie:sideChain
ArgB136136macie:sideChain
LysB3939macie:sideChain

Literature References

Notes:
Shaw JP
Determination of the structure of alanine racemase from Bacillus stearothermophilus at 1.9-A resolution.
Biochemistry 1997 36 1329-1342
PubMed: 9063881
Stamper GF
Reaction of alanine racemase with 1-aminoethylphosphonic acid forms a stable external aldimine.
Biochemistry 1998 37 10438-10445
PubMed: 9671513
Sun S
Evidence for a two-base mechanism involving tyrosine-265 from arginine-219 mutants of alanine racemase.
Biochemistry 1999 38 4058-4065
PubMed: 10194319
Watanabe A
Role of tyrosine 265 of alanine racemase from Bacillus stearothermophilus.
J Biochem 1999 125 987-990
PubMed: 10348897
Watanabe A
Tyrosine 265 of alanine racemase serves as a base abstracting alpha-hydrogen from L-alanine: the counterpart residue to lysine 39 specific to D-alanine.
J Biochem 1999 126 781-786
PubMed: 10502689
Ondrechen MJ
A model for enzyme-substrate interaction in alanine racemase.
J Am Chem Soc 2001 123 2830-2834
PubMed: 11456969
Watanabe A
Reaction mechanism of alanine racemase from Bacillus stearothermophilus: x-ray crystallographic studies of the enzyme bound with N-(5'-phosphopyridoxyl)alanine.
J Biol Chem 2002 277 19166-19172
PubMed: 11886871
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