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Search The CSA
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Catalytic Site Atlas

CSA LITERATURE entry for 2nmt

E.C. nameglycylpeptide N-tetradecanoyltransferase
SpeciesSaccharomyces cerevisiae (Baker's yeast)
E.C. Number (IntEnz) 2.3.1.97
CSA Homologues of 2nmtThere are 10 Homologs
CSA Entries With UniProtID P14743
CSA Entries With EC Number 2.3.1.97
PDBe Entry 2nmt
PDBSum Entry 2nmt
MACiE Entry 2nmt

Literature Report

Introduction
Mechansim
Reaction

Catalytic Sites for 2nmt

Annotated By Reference To The Literature - Site 1 (Perform Site Search)
ResidueChainNumberUniProtKB NumberFunctional PartFunctionTargetDescription
PheA170170macie:mainChainAmide
LeuA455455macie:mainChainCarbonyl
AsnA169169macie:mainChainAmide
LeuA171171macie:mainChainAmide

Literature References

Notes:
Bhatnagar RS
Structure of N-myristoyltransferase with bound myristoylCoA and peptide substrate analogs.
Nat Struct Biol 1998 5 1091-1097
PubMed: 9846880
Bhatnagar RS
The structure of myristoyl-CoA:protein N-myristoyltransferase.
Biochim Biophys Acta 1999 1441 162-172
PubMed: 10570244
Farazi TA
Structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoylCoA and peptide provide insights about substrate recognition and catalysis.
Biochemistry 2001 40 6335-6343
PubMed: 11371195
Farazi TA
Pre-steady-state kinetic studies of Saccharomyces cerevisiae myristoylCoA:protein N-myristoyltransferase mutants identify residues involved in catalysis.
Biochemistry 2001 40 9177-9186
PubMed: 11478885
Farazi TA
The biology and enzymology of protein N-myristoylation.
J Biol Chem 2001 276 39501-39504
PubMed: 11527981
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