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Search The CSA
PDB ID
UNIPROT ID
EC Number

Catalytic Site Atlas

CSA LITERATURE entry for 1b5t

E.C. namemethylenetetrahydrofolate reductase [NAD(P)H]
SpeciesEscherichia coli (Bacteria)
E.C. Number (IntEnz) 1.5.1.20
CSA Homologues of 1b5t1v93,1zp3,1zp4,1zpt,1zrq,2fmn,2fmo,3fst,3fsu,
CSA Entries With UniProtID P0AEZ1
CSA Entries With EC Number 1.5.1.20
PDBe Entry 1b5t
PDBSum Entry 1b5t
MACiE Entry M0120

Literature Report

Introduction
Mechansim
Reaction

Catalytic Sites for 1b5t

Annotated By Reference To The Literature - Site 1 (Perform Site Search)
ResidueChainNumberUniProtKB NumberFunctional PartFunctionTargetDescription
GluA2828macie:sideChain
AspA120120macie:sideChain

Annotated By Reference To The Literature - Site 2 (Perform Site Search)
ResidueChainNumberUniProtKB NumberFunctional PartFunctionTargetDescription
GluB2828macie:sideChain
AspB120120macie:sideChain

Annotated By Reference To The Literature - Site 3 (Perform Site Search)
ResidueChainNumberUniProtKB NumberFunctional PartFunctionTargetDescription
GluC2828macie:sideChain
AspC120120macie:sideChain

Literature References

Notes:
Trimmer EE
Folate activation and catalysis in methylenetetrahydrofolate reductase from Escherichia coli: roles for aspartate 120 and glutamate 28.
Biochemistry 2001 40 6216-6226
PubMed: 11371182
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